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U-47700 is an opioid analgesic drug developed by a team at Upjohn in the 1970s that acts as a selective agonist of the u-opioid receptor with a Kd value of 5.3 nM compared to 910 nM for the κ-opioid receptor and has around 7.5 x the potency of morphinein animal models
but u-477oo out of this market,Create new alternatives.better effect and higher purity,work well .
U-48800 is a structural isomer of the earlier opioid AH-7921 and the result of a great deal of work elucidating the quantitative structure–activity relationship of the scaffold. Upjohn looked for the key moieties which gave the greatest activity and posted over a dozen patents on related compounds, each optimizing one moiety until they discovered that U-48800 was the most active.
U-48800 became the lead compound of selective kappa-opioid receptor ligands such as U-50488, U-51754 (containing a single methylene spacer difference) and U-69,593, which share very similar structures. Although not used medically, the selective kappa ligands are used in research.
Compound purity :99%
Appearance :white powder
Application :For lab research
Storage: Keep in cool and dry place
Package: aluminium alloy bag or according to requirement
Type of shipping :EMS, TNT, FEDEX, DHL, UPS
Payment terms :T/T or Western Union or Money Gram or Bitcoin
Delivery time :Within 1-3 days
Production capacity :500kg/month
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